Dab tsi yog GenisteinPowder?
Genistein hmoovyog ib qho isoflavone compound tau los ntawm cov taum pauv. Nws yog thawj zaug txheeb xyuas thiab cais tawm ntawm genistein. Cov tshuaj synthesis ntawm genistein tau ua tiav thawj zaug hauv xyoo 1928 los ntawm Baker thiab Robinson. Raws li kev noj haus phytoestrogen, genistein muaj txiaj ntsig zoo hauv kev tiv thaiv kab mob plawv, tiv thaiv pob txha, thiab txhim kho cov kab mob metabolic thiab mob.
Khoom npe: | Genistein hmoov |
CAS Nr .: | 446-72-0 |
Cov mis mos molecular: | C15H10O5 |
Molecular Luj: | 270.23 |
Specification: | 98% |
Kev kuaj xyuas txoj kev: | HPLC |
Cov khoom zoo li: | Lub teeb daj hmoov siv lead ua, tawm-dawb hmoov siv lead ua |
Dej solubility: | Soluble nyob rau hauv ethanol thiab methanol, hardly soluble nyob rau hauv dej |
Metabolism ntawm Genistein Powder los ntawm plab hnyuv microbes:
Thiab cov khoom sib txawv ntawm cov dawb aglycones tsim los ntawm cov hnyuv microbe-mediated metabolism yog zoo sib xws hauv cov qauv. Daidzein yog metabolized rau hauv deoxymethylangolensin (O-Dma) lossis sib npaug ntawm cov kab mob hauv plab. Genistein yog metabolized los ntawm cov kab mob mus rau p-ethylphenol lossis 5-OH-equol. Genistein Powder yog thawj zaug hloov mus rau hauv dihydrogenistein los ntawm cov hnyuv tom qab nkag mus rau hauv txoj hnyuv. Dihydrogenistein yog degraded ntxiv nyob rau hauv txoj hnyuv los ntawm kev txo qis, lub nplhaib qhib, decolonization, thiab lwm yam kev cuam tshuam.
Dihydrogenistein hloov mus rau p-hydroxy-phenyl propionic acid los ntawm lub nplhaib-qhib, ua raws li kev txo qis thiab tshem tawm pawg los tsim cov metabolites xws li L-5-hydroxy-equol.
Equol yog yooj yim absorbed los ntawm lub plab tshaj lwm yam metabolites. Thiab nrog rau -estrogen receptor (-estrogen receptor, ER) muaj peev xwm ua kom muaj zog. Yog li, genistein muaj ntau dua estrogenic kev ua haujlwm. Yog li, nws muaj lub cev muaj zog ntawm kev tiv thaiv thiab kho cov pob txha pob txha, txo kev pheej hmoo ntawm cov hlab plawv thiab lwm yam kab mob, thiab cuam tshuam rau kev tso tawm ntawm insulin.
Genistein Powder Benefits:
Tswj cov tshuaj insulin
Cov kev tshawb fawb tau pom tias cov hmoov ntshiab genistein muaj peev xwm tiv thaiv beta hlwb thiab txhim kho insulin secretion nyob rau hauv cov tsiaj thiab cellular qauv. Isoflavones txhawb kev tsim cov tshuaj insulin los ntawm kev ua kom insulin receptor substrate 1 thiab cAMP txoj hauv kev. Phosphorylation thiab ua kom cov protein kinase B ua rau kom muaj zog insulin secretion. Thaum lub sij hawm ua kom cov txheej txheem, cov protein kinase B txoj kev txhawb kev sib tw ntawm lub forkhead box (FOX01) protein thiab forkhead box protein A2 thaum lub sij hawm ua kom cov txheej txheem. Txhim kho kev nthuav qhia ntawm pdx1, tus thawj tswj hwm ntawm pancreatic -cell loj hlob, ua rau -cell proliferation.
Genistein ua rau glucagon-zoo li peptide -1 receptor txoj kev los ntawm inhibiting lub nuclear NF-κB txoj kev. Ua kom cov mitogen-activated protein kinase (MAPKK) thiab cov protein kinases ua rau phosphorylation ntawm extracellular regulated protein kinases los txhawb -cell ciaj sia taus thiab proliferation.
tswj lipogenesis
Kev noj zaub mov kom tsawg thiab poob phaus los ntawm genistein tshwm sim vim qhov txo qis ntawm leptin, qhov tseem ceeb tshaj plaws adipose-derived hormone. Ua lub luag haujlwm tseem ceeb hauv kev tswj hwm kev siv zog thiab kev siv hluav taws xob los ntawm kev tswj kev qab los noj mov thiab cov metabolism. Leptin ntau lawm yog proportional rau roj cia thiab ua los ntawm nws cov receptor, leptin receptor. Muaj ntau yam subtypes ntawm leptin receptors, uas leptin receptor B tau pom tias yog qhov tseem ceeb rau leptin kev ua. Cov nyhuv leptin feem ntau ua haujlwm nyob rau hauv lub hauv nruab nrab lub paj hlwb, tshwj xeeb tshaj yog nyob rau hauv lub hypothalamus qhov twg leptin receptor B mRNA yog heev nthuav.
Yuav qhov twgGenistein hmoov?
Yansheng International Group Ltd. muaj ntau tshaj 16 xyoo ntawm kev tsim, R & D, thiab kev muag khoom. Muaj cov neeg siv khoom thoob plaws ntiaj teb. Peb ib txwm hais kom muab cov khoom zoo thiab kev pabcuam rau txhua tus neeg siv khoom! Thov hu rau cov kws tshaj lij genistein manufacturers ncaj qha rau nplooj ntawv no lossismedical@ysgcn.com
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