Puas yog Arbutin Safe?

Lub hauv paus ntsiab lus ntawm whiteningarbutin yog tias cov piam thaj residue yog hydrophilic, thiab phenolic hydroxyl pawg muaj cov nyhuv inhibiting melanin synthase. Yog li ntawd, raws li ib tug whitening additive nrog ib tug whitening nyhuv, nws muaj peev xwm muab ntxiv rau whitening tshuaj pleev ib ce rau ib tug tej yam - moisturizing thiab whitening nyhuv. Tab sis, arbutin puas nyab xeeb?

Puas yog Arbutin Safe?

Cov kws tshawb fawb tau kawm txog cov nyhuv hauv vitro inhibitory thiab cytotoxicity ntawm tyrosinase kev ua haujlwm ntawm tsib yam tshuaj dawb huv, xws li arbutin, Vic, VitC derivatives, hydrogen aldehyde, thiab kojic acid, thiab xaus lus tias ntawm tsib tus neeg ua kom dawb huv, Arbutin yog qhov nyab xeeb thiab zoo tshaj plaws. siv tau.

Cov teebmeem lom ntawm arbutin rau ntawm daim tawv nqaij melanocytes kuj pom tau tias -arbutin tuaj yeem rhuav tshem kev loj hlob ntawm melanocytes thiab inhibit kev loj hlob ntawm cov hlwb, qhia tias cytotoxicity yuav tsum tsis txhob ignored.

Txoj kev tshawb fawb tam sim no kuj pom tias -arbutin tuaj yeem ua rau cov cell membrane ntawm cov kab lis kev cai, yog li tus nqi ntawm -arbutin muaj qee yam kev sib raug zoo nrog nws txoj kev nyab xeeb. Tam sim no, qhov ntau npaum ntawm -arbutin hauv tshuaj pleev ib ce yog li 3 feem pua. Yog tias qhov ntau npaum li cas tsawg dua li qhov no, cov nyhuv inhibitory ntawm catalytic kev ua ntawm tyrosinase hauv daim tawv nqaij tsis muaj zog, thiab cov nyhuv whitening tsis pom tseeb. kev loj hlob, ua rau cytotoxicity. Cov kws tshawb fawb Nyij Pooj tau ua cov kev sim siv tib neeg lub hlwb los qhia tias -arbutin tsim los ntawm biotechnology yog 10 npaug zog dua li -arbutin feem ntau muab rho tawm los ntawm Wufanshu hauv inhibiting melanin ntau lawm, thiab muaj zog dua lwm yam kev ua kom dawb huv tam sim no. Element. Nws tsis cuam tshuam rau kev loj hlob ntawm cov hlwb ntawm ntau dua, yog li qhov ua tau zoo thiab kev nyab xeeb yog siab dua -arbutin.

Kev sib piv nrog lwm cov tawv nqaij depigmented:

Azelaic acid, kojic acid thiab nws cov derivatives, hydroquinone, thiab lwm yam. inhibit tyrosinase kev ua si thiab txo melanin ntau lawm los ntawm kev sib tw thiab / lossis tsis sib tw; vitamin C thiab nws cov derivatives, a-lipoic acid, a-tocopherol phenol

Lwm tus cuam tshuam nrog melanin synthesis los ntawm cov teebmeem antioxidant; retinoic acid tiv thaiv kev thauj ntawm melanin mus rau corneal hlwb, ua rau hypopigmentation; unsaturated fatty acids tuaj yeem txhawb kev rov ua dua tshiab ntawm tes thiab txhawb nqa cov keratinocytes uas muaj melanin granules, ua rau depigmentation. ; Qee cov tshuaj suav tshuaj monomers lossis cov ntawv sau tshuaj ua lub luag haujlwm ntawm decolorizing tus neeg sawv cev los ntawm ntau txoj kev.

Ntawm lawv, VitC txhaj tshuaj thiab hydroquinone muaj qhov siab tshaj plaws inhibition tus nqi ntawm tyrosinase kev ua, thiab qis tshaj concentration ntawm ib nrab inhibition, yog li cov nyhuv whitening yog qhov zoo tshaj plaws. Txawm li cas los xij, hauv kev siv tswv yim, vim muaj zog cytotoxicity ntawm hydroquinone, nws yuav ua rau daim tawv nqaij mus tas li depigmentation, uas tau maj mam tshem tawm. Cov nyhuv whitening ntawm VitC muaj kev sib raug zoo nrog nws cov qauv thiab lub xeev. Feem ntau, tsuas yog levorotatory Vit C muaj cov nyhuv whitening. VitC yog dej-soluble, tsis yooj yim nkag mus rau hauv stratum corneum ntawm daim tawv nqaij, thiab yooj yim oxidized thiab tsis ruaj khov, yog li nws daim ntawv thov raug txwv. Nws feem ntau yog ua ke nrog cov hlau xws li sodium thiab calcium kom nws ruaj khov, los yog siv cov tshuaj pleev ib ce hauv daim ntawv ntawm nws cov derivatives.

Arbutin muaj cov nyhuv whitening zoo, kuj me me cytotoxicity, thiab ruaj khov zog, yog li nws yog cov feem ntau siv whitening neeg sawv cev tam sim no. Kev siv cov tshuaj arbutin tuaj yeem txo cov qib pigmentation ntawm melasma thiab txo qhov chaw ntawm daim tawv nqaij.

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